His life spanned a period of significant change, during which the cultural influences of Hellenism deeply permeated the Eastern Mediterranean, impacting religious and philosophical paradigms. Philo's work is characterised by an intricate synthesis of Jewish theology and Stoic, Platonic, and Aristotelian thought.

Central to his philosophy is the belief in a transcendent God, which he articulated through allegorical interpretations of the Hebrew Scriptures. This approach not only redefined the understanding of Jewish texts but also laid foundational ideas that would later resonate through Christian thought. Philo's legacy continues to influence theological discourse, illustrating the enduring dialogue between faith and reason, and the complexities of cultural exchange in the ancient world.